A Pilot Study: Safety & TOlerability of Hypertonic Saline Administration Via IntraOsseous Access "IntraOsseous"


Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- NCCU patients in which osmotherapy with HTS is planned (standard of care
- Does not already have a CVC or PICC.

Exclusion Criteria

- <18 years old
- Known pregnancy
- Long bone fracture in the targeted site
- Proximity to prosthetic joint
- Excessive tissue/absence of anatomical landmarks
- History of osteopetrosis
- Previous significant orthopedic procedure at site
- Prosthetic limb or joint
- IO catheter use in the past 48 hours of the target bone
- Infection at the area of insertion
- Hypersensitivity to lidocaine