A Longitudinal Study of Function and Participation in Patients With Stroke

Recruiting

Phase N/A Results N/A

Trial Description

A longitudinal study of function and participation in patients with stroke: An integrated brain imaging and biomechanical analysis

Detailed Description

Brain damage may lead to various motor deficits, which further influence the function and participation. Cerebral vascular accident (CVA) is the common disorder for acquired brain damage. Neural network in patients with brain damage could also be used to determine their clinical behavior by identifying altered neural network associated with behavioral improvement. The investigators hypothesize that the level of brain image and biomechanical will change with time in patients with stroke. Under this hypothesis, the measures of biomechanical change are correlated with neural changes. The aim of this study is to investigate the function and participation in patients with stroke evaluated by clinical measures, biomechanical, psychological, physiological and multimodal brain image. The primary goal of this study is to establish, evaluate and follow-up biomechanical- and image-based biomarkers for the impairment of function and participation information processing present in patients with stroke.

Conditions

Trial Design

  • Observation: Cohort
  • Perspective: Prospective
  • Sampling: Non-Probability Sample

Trial Population

Control and experimental groups

Outcomes

Type Measure Time Frame Safety Issue
Primary Change from baseline of biomechanical measurement for Healthy adult and patients with stroke in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of functional magnetic resonance imaging (fMRI) analysis in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of psychological in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of body composition in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of severity in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of body in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of activity in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of participation in 6 months and 12 months baseline, 6 months, 12 months No
Secondary Change from baseline of quality of life in 6 months and 12 months baseline, 6 months, 12 months No

Sponsors