BASICS
Basilar Artery International Cooperation Study
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Status:
Completed. As of September 2007, 624 patients had been enrolled at 49 centers worldwide. Data is being analyzed and results will be available in May 2008.
Purpose:
To obtain sufficient information about the response of basilar stroke patients to various therapies to eventually design a randomized controlled trial.
Location(s):
Europe, North America, South America, Asia, Australia
Year Started:
2002
Year Finished:
2006
Design:
Prospective observational multicenter database.
Inclusion Criteria
Patients with radiologically confirmed symptomatic basilar artery occlusion will be eligible for this trial.
Patient Involvement:
All patients will be clinically evaluated and will receive standard care according to their physicians' discretion.
Primary Outcome:
Patients will be sorted into three groups -- those who have received antithrombotics, those who have received intravenous thrombolytics, and those who have received intraarterial thrombolytics -- and will be analyzed with respect to the mortality rate, the incidence of poor clinical outcome (modified Rankin scale 4-5), and the frequency of good clinical outcome (modified Rankin scale 0-3).
Results:
Study Outcomes From November 2002 until December 2006 data have been collected on 400 patients, from 42 centers in 12 countries. Most patients were treated with IA therapy (55%), followed by antithrombotics (29%) and IV thrombolysis (6%). The overall mortality was 45%.
Source of Information:
Presented at 12th European Stroke Conference [May 2003]. Presented at the 30th International Stroke Conference [February 2005].
Presented at 14th European Stroke Conference [May 2005].
Presented at the 2006 International Stroke Conference [February 2006].
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Web Links and Publications:
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This information last updated on: 9/28/2009
Reviewed on: 05/19/2009.
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