Stroke Trials Registry

Perindopril
Aceon Coversyl

Action
Antihypertensive; angiotensin converting enzyme (ACE) inhibitor

Status
Available in US for treatment of hypertension. Multicenter trial for stroke prevention ongoing.

Trial(s)
= Ongoing
= Completed

HYVET Hypertension in the Very Elderly Trial

PROGRESS Perindopril Protection Against Recurrent Stroke Study

Web Links and Publications

Internet Stroke Center: PROGRESS trial results and data. Click here for additional references, web resources, and slide presentations.

PROGRESS Trial Web Site

Aceon® (perindopril) Web Site.

Solvay Web Site.

Effects of a Perindopril-Based Blood Pressure Lowering Regimen on the Risk of Recurrent Stroke According to Stroke Subtype and Medical History
Stroke 2004;35:116-121.

Effects of a Perindopril-Based Blood Pressure-Lowering Regimen on Disability and Dependency in 6105 Patients With Cerebrovascular Disease.
Stroke 2003;34:xx-xx.

The Perindopril Protection Against Recurrent Stroke Study (PROGRESS): Clinical Implications for Older Patients with Cerebrovascular Disease.
Drugs Aging 2003;20(4):241-51

Effect of perindopril on cerebral and renal perfusion in stroke patients with carotid disease.
Stroke 2001 Feb;32(2):473-8

Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.
Lancet. 2001 Sep 29;358(9287):1033-41.

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