Internet Stroke Center Home Stroke Trials Registry
 
National Institute of Neurological Disorders & Stroke
American Stroke Association
Washington University School of Medicine
 
Trials Directories
Ongoing Trials
Completed Trials
Acute Stroke Trials
Hemorrhage Trials
Prevention Trials
Recovery Trials
Interventions
Drugs - By Name
Drugs - By Category
Procedures
Recovery Therapies
Assessment Scales
Specific Stroke Scales
Stroke Scales Overview
Stroke Trial Links
Government Sites
Independent Sites
News & Updates
Update List
General Stroke News
About this Site
Submit Your Trial
Send Feedback
Search for Trials
PubMed
We comply with the "Health on the Net" (HON) code of standards for trustworthy health information: verify here.



 
Stroke Interventions in Clinical Trials
Printable Version
Prourokinase
Prolyse® Nasaruplase beta

Action
Thrombolytic agent (urokinase pro-drug, recombinant)

Status
Phase II trial (PROACT) complete; results reported January 1998. Multicenter trial (PROACT II) results presented 2/99, final report published 11/99. PROACT II demonstrated significant benefit for Pro-urokinase compared to control. PROACT III trial planned but status unknown.

Trial(s)
  = Ongoing
  = Completed

PROACT II Prolyse in Acute Cerebral Thromboembolism II
PROACT I Prolyse in Acute Cerebral Thromboembolism Trial

Web Links and Publications
Abbott Laboratories Web Site.
Overview of Cochrane thrombolysis meta-analysis.
Neurology. 2001;57(5 Suppl 2):S69-76. Review.
Effect of Intraarterial Prourokinase on CT Infarct Volume: Results of Proact II.
Stroke 2000 31(1): 278

UID: 35

   

Internet Stroke Center at Washington University:
HOME | ABOUT | PRIVACY POLICY | CONTACT

Copyright © 1997-2010 - Internet Stroke Center. All rights reserved.                                           Last modified: Friday, March 12, 2010