Eponym
Dejerine Syndrome
Anatomy
Medulla: Medial medulla
Vascular
- Vertebral artery: Anteromedial artery
- Anterior spinal artery: Anteromedial artery
- Basilar artery
Signs & Symptoms
| Side | Manifestation | Comments |
|---|---|---|
| Contralateral | Weakness – upper and lower extremity | Pyramidal tract |
| Contralateral | Hemisensory loss – vibration and proprioception | Medial lemniscus |
| Ipsilateral | Tongue weakness +/- atrophy | Cn 12 nucleus |
Notes
Rare stroke syndrome (<1% of vertebrobasilar strokes, Bassetti et al., 1994). Medial medullary infarct is associated with clinical triad of ipsilateral hypoglossal palsy, contralateral hemiparesis, and contralateral lemniscal sensory loss. Variable manifestations may include isolated hemiparesis, tetraparesis, ipsilateral hemiparesis, I or C facial palsy, ataxia, vertigo, nystagmus, dysphagia. Palatal and pharyngeal weakness rare in pure MMI, common in lateral medullary infarct.
References
- Medial medullary stroke: report of seven patients and review of the literature. Neurology 1997 Apr;48(4):882-90.
- Dejerine, J. Semiologie des affections du systeme nerveux. Paris: Masson, 1914.