Evidence-Based
Use of Antithrombotic Therapy
in the Prevention of Cardioembolic Stroke Allyson Zazulia, M.D. -- Departments
of Neurology and Radiology
Washington University School of Medicine -- Presented July
18, 2006
Other parenteral
antithrombotics
•
Argatroban (thrombin
inhibitor)
phase 2 dose-escalation trial of 2 doses argatroban
in combination with tPA (TARTS) ongoing
• Abciximab
(monoclonal Ab against platelet glycoprotein Gp IIb-IIIa
receptor)
phase 3 RCT (AbESTT-II) halted 10/05 due to "safety
concerns"
