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ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group.
Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).
JAMA 2002 Dec 18;288(23):2998-3007.

American-Canadian Co-Operative Study Group.
Persantine Aspirin Trial in cerebral ischemia. Part II: Endpoint results.
Stroke 1985; 16:406-415
Stroke Trials Directory Entry: Persantine Aspirin Trial

Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients.
BMJ 2002; 324:71-86.

Antonio L. Dans; Leonila F. Dans; Gordon H. Guyatt; Scott Richardson; for the Evidence-Based Medicine Working Group.
Users' Guides to the Medical Literature: XIV. How to Decide on the Applicability of Clinical Trial Results to Your Patient
JAMA 1998;279:545-549.

Berge E, Abdelnoor M, Nakstad PH, Sandset PM. Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study. HAEST Study Group. Heparin in Acute Embolic Stroke Trial. (HAEST)
Lancet 2000; 355:1205-1210
Stroke Trials Directory Entry: HAEST

Bousser MG, Eschwege E, Haguenau M, et al; "AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia.
Stroke 1983; 14:5-14
Stroke Trials Directory Entry: AICLA

Broderick JP, Adams HP Jr, Barsan W, et al. Guidelines for the management of spontaneous intracerebral hemorrhage: A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association.
Stroke 1999 Apr;30(4):905-15.

CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE).
Lancet 1996 Nov 16;348(9038):1329-39.
Stroke Trials Directory Entry: CAPRIE

Cardiac Arrhythmia Pilot Study (CAPS) Investigators. Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS.
Am J Cardiol. 1988 Mar 1;61(8):501-9.

Chimowitz MI, Kokkinos J, Strong J,  et al. Warfarin-Aspirin Symptomatic Intracranial Disease Study (WASID).
Neurology 1995; 45: 1488-1493.
Stroke Trials Directory Entry: WASID

Chimowitz MI, Lynn MJ, Howlett-Smith H, et al; Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. Warfarin-Aspirin Symptomatic Intracranial Disease Trial Investigators.
NEJM 2005 Mar 31;352(13):1305-16.

Clark WM, Wechsler LR, Sabounjian LA, Schwiderski UE; Citicoline Stroke Study Group.A phase III randomized efficacy trial of 2000 mg citicoline in acute ischemic stroke patients.
Neurology 2001 Nov 13;57(9):1595-602.
Stroke Trials Directory Entry: Citicoline ECCO 2000

Clark WM, Williams BJ, Selzer KA, Zweifler RM, Sabounjian LA, Gammans RE. A randomized efficacy trial of citicoline in patients with acute ischemic stroke.
Stroke 1999 Dec;30(12):2592-7.
Stroke Trials Directory Entry: Citicoline 007

Dans AL, Dans LF, Guyatt GH, Richardson S.  Users' guides to the medical literature: XIV. How to decide on the applicability of clinical trial results to your patient. Evidence-Based Medicine Working Group.
JAMA 1998 Feb 18;279(7):545-9.

Diener HC, Cunha L, Forbes C, et al; European Stroke Prevention Study. 2. Dipyramidole and acetylsalicylic acid in the secondary prevention of stroke.  
J Neurol Sci. 1996 Nov;143(1-2):1-13.
Stroke Trials Directory Entry: ESPS2

Diener HC. Dipyridamole trials in stroke prevention.
Neurology 1998; 51(Suppl 3):S17-S19

Diener HC, Bogousslavsky J, Brass LM, et al; MATCH investigators. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial.
Lancet 2004 Jul 24-30;364(9431):331-7.
Stroke Trials Directory Entry: MATCH

Drummond MF, Richardson WS, O'Brien BJ, Levine M, Heyland D.
Users' guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. A. Are the results of the study valid? Evidence-Based Medicine Working Group.
JAMA 1997; 277:1552-1557.

Echt DS, Liebson , PR Mitchell, et al. Cardiac Arrhythmia Suppression Trial (CAST) Investigators. Mortality and morbidity in patients receiving encainide, flecainide, or placebo.
NEJM 1991 Mar 21;324(12):781-8.

Feinstein AR, Horwitz RI. Problems in the "Evidence" of "Evidence-Based Medicine."
Am J Med 1997;103:529-535

Gibbs JM, Wise RJ, Thomas DJ, Mansfield AO, Russell RW.
Cerebral haemodynamic changes after extracranial-intracranial bypass surgery.
J Neurol Neurosurg Psychiatry. 1987 Feb;50(2):140-50.

Gorelick PB. Carotid endarterectomy: where do we draw the line?
Stroke 1999 Sep;30(9):1745-50.

Grodstein F, Clarkson TB, Manson JE. Divergent Data on Post-Menopausal Hormone Therapy.
NEJM 2003; 348:645-650.

Gross DE, Brenner SL, Esformes I, Gross ML.
Arthroscopic treatment of degenerative joint disease of the knee.
Orthopedics. 1991 Dec;14(12):1317-21.

Guiraud-Chaumeil B, Rascol A, David J, et al; Prevention of recurrences of cerebral ischemic vascular accidents by platelet antiaggregants. Results of a 3-year controlled therapeutic trial.
Rev Neurol (Paris). 1982;138(5):367-85.

Guyatt GH, Haynes RB, Jaeschke RZ, et al;  Users' Guides to the Medical Literature: XXV. Evidence-based medicine: principles for applying the Users' Guides to patient care. Evidence-Based Medicine Working Group.
JAMA 2000 Sep 13;284(10):1290-6.

Guyatt GH, Sackett DL, Cook DJ. Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group.
JAMA 1993; 270:2598-2601.

Guyatt G, Schunemann H, Cook D, Jaeschke R, Pauker S, Bucher H; American College of Chest Physicians. Grades of recommendation for antithrombotic agents.
Chest 2001; 119:3S-7S.

Hass WK Easton JD, Adams HP, et al.
A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. Ticlopidine Aspirin Stroke Study Group.
Stroke 321:501-507.

Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group.
JAMA 1994; 271:59-63.

Moseley JB, O'Malley K, Petersen NJ, et al.
A controlled trial of arthroscopic surgery for osteoarthritis of the knee.
NEJM 2002 Jul 11;347(2):81-8.

Moses JW, Leon MB, Popma JJ, et al; SIRIUS Investigators.
Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.
NEJM 2003 Oct 2;349(14):1315-23.

NINDS t-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. 
Stroke 1997; 28:2109-2118.

NINDS t-PA Stroke Study Group. Tissue Plasminogen Activator for Acute Ischemic Stroke (NINDS). NEJM 1995; 333:1581-1587
Stroke Trials Directory Entry: NINDS-tPA Stroke Trial

Powers WJ, Martin WR, Herscovitch P, Raichle ME, Grubb RL Jr.
Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects.
Neurology. 1984 Sep;34(9):1168-74.

Rothwell, PM. Treating individuals 2. Subgroup analysis in randomised controlled trials: importance, indications, and interpretation.
Lancet 2005 Jan 8-14;365(9454):176-86.

Samson Y, JC Baron, MG Bousser, et al.
Effects of extra-intracranial arterial bypass on cerebral blood flow and oxygen metabolism in humans
Stroke 1985 16: 609-616.

Smith, WS, Sung G, Starkman S, et al. J for the MERCI Trial Investigators.
Safety and Efficacy of Mechanical Embolectomy in Acute Ischemic Stroke: Results of the MERCI Trial.
Stroke 2005 36:1432 - 1438.