William J. Powers, M.D.--Departments of
Neurology, Neurosurgery and Radiology
Washington University School of Medicine -- Presented July
11, 2006
In this series of lectures, we
will discuss the current state of
evidence
supporting different treatments for the
most common types of
cerebrovascular disease.
The evidence that we will consider is
based on studies that describe
the association
between treatments and clinical outcomes in human
subjects.
Such empirical data
require no assumptions regarding mechanisms
of
disease or treatment effects. Since they require no
assumptions,
they are the most valid means to judge
the efficacy of therapeutic
interventions.
Users' Guides to the Medical Literature:
XXV. Evidence-based medicine: principles for applying
the Users' Guides to patient care. Evidence-Based Medicine
Working Group.
Guyatt GH, Haynes RB, Jaeschke RZ, Cook DJ, Green L, Naylor
CD, Wilson MC, Richardson WS.
JAMA. 2000 Sep 13;284(10):1290-6