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The "Golden Hour" of Acute Ischemic Stroke

Post-Treatment Guidelines & Recommendations

Post Treatment Care - Antihypertensive Therapy
  

SBP 180 - 230 or
DBP 105-120 mm Hg

  • Labetalol 10 mg IV, may repeat / double to 150 mg max
  • Labetalol drip 2-8 mg / min

SBP > 230 or
DBP 121 - 140 mm Hg

  • Above
  • Sodium nitroprusside   

 DBP > 140 mm Hg

  • Sodium nitroprusside (0.5 ug/kg per minute)   


May consider enalapril in patients with CHF, asthma, abnormal cardiac conduction

Check with current guidelines

 

ICH Contingency Plan

  • CT Stat CT
  • STAT labs
    > (fibrinogen, CBC, PT/PTT)
  • Type and screen
  • Fresh frozen plasma
  • Neurosurgical consult

 

Management of Seizures

Prophylactic anticonvulsant medication not recommended

Recurrent seizures require treatment

  • Diazepam 5 mg over 2 minutes
  • Lorazepam 1-4 mg over 2–10 minutes
  • Follow benzodiazepines with longer acting anticonvulsant (phenytoin, phenobarbital, etc.)

 

Pneumonia After Stroke

  • One third of stroke patients develop a pneumonia within 1 month
  • 3rd leading cause of death in the first month
  • Estimated cost per event $10,000 and a 7 day length of stay
  • Laryngeal cough reflex cough tests can identify patients at risk

Source: Addington, Stroke 1999

Rehabilitation

Early rehabilitation is key for recovery

Early mobilization also prevents:

  • Deep venous thromboses and pulmonary emboli
  • Decubitus ulcers
  • Contractures
  • Malnutrition
  • Pneumonias
  • UTI

 

What do you need to treat?

  • Preplanning and preparation
  • Multidisciplinary approach
  • Know the mechanics
  • Know the risks
  • Coordinated post-treatment care

 

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This presentation was written by Dr. Edward C. Jauch of the Greater Cincinnati / Northern Kentucky Stroke Team at the University of Cincinnati College of Medicine.

Last Revised: March 26, 2001

 

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