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Notes:
The rate of major bleeding (excluding ICHs) rose only from 5.2% to 6.4%.
Thus, for every 100 patients like mine whom we add ASA to, we expect to prevent 3 nonfatal strokes, 5 deaths and cause only 1 major nonfatal bleed!
See also: Laffort P. et al. Early and long-term (one-year) effects of the association of aspirin and oral anticoagulant on thrombi and morbidity after replacement of the mitral valve with the St. Jude medical prosthesis: a clinical and transesophageal echocardiographic study. J Am Coll Cardiol 2000;35:739-46.
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This presentation was authored by Dr. Brian Gage of the Washington University School of Medicine.
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