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Stroke in Perspective: Risk Factors

Percent of Each Stroke Type Preceded by TIA

Percent of Each Stroke Type Preceded by TIA

Every year approximately 50,000 people in the United States experience transient ischemic attacks (TIAs) and about a third of them will develop a stroke [Feinberg  WM, et al, 1994.]

TIAs have bee vigorously defined.  According to the Ad Hoc Committee on Guidelines for the Management of Transient Ischemic Attacks of the Stroke Council of the American Heart Association, TIAs are "temporary focal brain or retinal deficits caused by vascular disease that clear completely in less than 24 hours."  The Committee notes, however, that the 24-hour limit is arbitrary and that most TIAs are much shorter, the majority clearing within 1 hour.  

In the Cooperative Study of Transient Ischemic Attacks, the median duration of carotid distribution TIAs was 14 minutes and that of vertebrobasilar TIAs was 8 minutes [Dyken ML, et all. JAMA. 1977;237:882.]

TIAs have diverse causes.  In older patients and those with cerebrovascular risk factors, atheroscelerosis of the arteries supplying the brain is the most frequent cause.  TIAs are most common in patients with large-artery atherothrombotic disease, with embolism being the second most likely type of stroke to be preceded by a TIA.  The attacks can occur days, weeks, or even months before a major stroke.

  

  

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From: Acute Ischemic Stroke: New Concepts of Care
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