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Odds Ratios for Ischemic Stroke
by Age
(in Relation to TIA, Current Cigarette Smoking, or Hypertension
with 95 CIs)
Rochester Epidemiology Project,
1970-84
The Rochester Epidemiology Project identified
all patients with documented diagnoses of first ischemic stroke
during the period 1970-1984. Matching cases with controls
from he population on a 1:1 basis resulted in 931 cases and
controls (matched pairs).
The data indicated that the presence of TIA,
current cigarettes smoking, hypertension, or atrial fibrillation
(see below) greatly increases the risk of ischemic stroke
at younger ages. At older ages, however, these factors
increased the risk of ischemic stroke by a lesser amount.
The interrelationships among atrial fibrillation,
hypertension, and age, as they affect the incidence of ischemic
stroke, were complex. For non-hypertensive persons,
the incidence of ischemic stroke was 7-fold higher for those
with persistent atria fibrillation than for those without
atrial fibrillation or those with intermittent atrial fibrillation.
For hypertensive persons, however, the odds ratio comparing
intermittent and persistent atrial fibrillation with no atrial
fibrillation were similar, independent of age.
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Stroke Education
