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Stroke in Perspective: Risk Factors

Ischemic Stroke and Intracerebral Hemorrhage Mortality Rates in Men

According to Diastolic BP and Serum Cholesterol Levels

Ischemic Stroke and Intracerebral Hemorrhage Mortality Rates in Men

The relationship of total serum cholesterol and ischemic stroke is unclear and inconsistent.  Data from the Framingham Study showed no clear influence of total cholesterol on the incidence of atherothrombotic brain infarction [Wolf PA, et al, 1992].

However, the Multiple Risk Factor Intervention Trial (MRFIT) provided evidence for a direct relationship between high levels of serum cholesterol and ischemic stroke, particularly in hypertensive men [Iso H, et al, 1989].  At the same time, there was also evidence of a relationship between low total serum cholesterol and increased incidence of intracerebral hemorrhage (ICH) in men with diastolic blood pressure above 90 mmHg.

 

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From: Acute Ischemic Stroke: New Concepts of Care
© 1998-1999 Genentech Inc. All rights reserved.
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