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Stroke in Perspective: Risk Factors

Death Rates for Stroke per 100,000 Population

Groups Defined by Race, Age, and Gender:  1993

Groups Defined by Race, Age, and Gender:  1993

It is apparent that the stroke death rate for specified age groups in 1993 was higher for African-American men and women than it was for Caucasian men and women.  The ratio of age-adjusted death rates for African Americans as compared to Caucasians (all genders) was 1.49.

The National Health and Nutrition Examination Survey I: Epidemiologic Follow-Up Study (NHEFS) compared mortality rate ratios of African-American versus Caucasian persons, aged 35 through 77 years, before and after adjustment for different risk factors [Otten MW, et at. JAMA. 1990;263:845].  The overall age-adjusted mortality rate ratio (African Americans/Caucasians) was 1.32.  The ratio for death due to stroke was 1.98, making stroke the disease category that accounted for the greatest percent difference in mortality rate between two populations.  The data suggested that 31% of the total excess mortality in African Americans (age 35-45) could be accounted for by known risk factors for cardiovascular disease (smoking, systolic blood pressure, cholesterol level, body-mass index, alcohol intake, and diabetes); a further 38% could be accounted for by family income, leaving 31% of the excess African-American total mortality unexplained.  The association between family income and excess mortality was not fully unexplained, but the investigators suggested that some of the increased prevalence of high blood pressure and overweight may be a reaction to the "stresses of being poor."  Although lack of health care access could be a factor, some data have indicated that poverty carried excess mortality risks that were largely unexplained unequal health care or social networks [Haan M, et al. Am J Epidemiol. 1987;125:989].

The epidemiology of stroke among Hispanics in the United States has only begun to be investigated.  A study examining data from the National Center for Health Statistics found that stroke mortality rates were similar in Hispanic-Americans and other Caucasian populations aged 45 to 64 years; at ages 65 and over, Hispanics had rates that were substantially lower [Gillum RF. Stroke 1995;26:1701-12].  It is suggested that ethnic differences in stroke mortality may be due in part to lower blood pressure in Hispanics than non-Hispanics.

  

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From: Acute Ischemic Stroke: New Concepts of Care
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