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Atherosclerosis and Thrombus Formation
Physiologic Subtypes of Thrombosis-Related
Ischemic Stroke
Thrombosis is a common link between
three subtypes of ischemic stroke, each having a different
etiology.
Athero- thrombotic occlusion of
larger arteries (eg, carotid, middle cerebral, basilar) is
not only the most common cause of primary large vessel occlusive
cerebrovascular disease, but also is the most common cause
of stroke.
After primary large vessel occlusive
disease, embolism is the most common cause of stroke.
Most embolic strokes are due to cerebral arterial atherothrombosis,
in which a larger thrombus and is carried to other places
in the cerebrovasculature. Cerebral emboli may also
arise from other cardiogenic sources and deep vein thrombosis.
Primary small vessel cerebrovascular
disease most prominently causing lacunar strokes arises from
microatheroma of an influx of fat-like materials (lipohyalinosis).
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Stroke Education
